COURSE INTRODUCTION AND APPLICATION INFORMATION


Course Name
Current Topics in Immunology and Cancer
Code
Semester
Theory
(hour/week)
Application/Lab
(hour/week)
Local Credits
ECTS
MED 310
Fall/Spring
3
0
3
4
Prerequisites
None
Course Language
English
Course Type
Elective
Course Level
First Cycle
Mode of Delivery -
Teaching Methods and Techniques of the Course
Course Coordinator
Course Lecturer(s)
Assistant(s) -
Course Objectives This course aims to inform students about the latest topics in immunology by focusing on cancer.
Learning Outcomes The students who succeeded in this course;
  • 1. Define the concepts and terms about immunology and cancer.
  • 2.Describe the cells and tissues of the immune system with their functions.
  • 3. Explain antigen presentation and complement response mechanisms.
  • 4. Explain natural, acquired and mucosal immunity.
  • 5. Explain immunology of transplantation, immune tolerance, autoimmunity and immune regulation concepts and relation to disorders.
  • 6. Define the state of tumor dormancy.
  • 7. Explain examples of cancer-specific immune responses and their use in cancer treatment.
Course Description This course begins with a general introduction to the mechanism of antigen delivery, which is a summary of the innate and adaptive immune system and complement system, which aims to cover the functioning of the immune system cells and tissues and then the basic mechanisms of the immune system as a whole. The course will focus on the main mechanisms of tumor immune response.
Related Sustainable Development Goals

 



Course Category

Core Courses
Major Area Courses
X
Supportive Courses
Media and Managment Skills Courses
Transferable Skill Courses

 

WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES

Week Subjects Required Materials
1 Introduction to the Immune system: Cells and Tissues of the Immune System Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 9th Edition Chapter 1 and 2 p 1-35
2 Antigens and Antigen Presentation Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 9th Edition Chapter 6 p 117-145
3 Innate Immune System Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 9th Edition Chapter 4 p 51-87
4 Adaptive Immunity: T cells Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 9th Edition Chapter 8, 9, 10 and11 p 171-239
5 Adaptive Immunity: B cells Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 9th Edition Chapter 8, 12 and 13 p 239-289
6 Activation and Regulation of the Complement System Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 9th Edition Chapter 13 p 272-287
7 Mucosal Immunity Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 9th Edition Chapter 14 p 289-311
8 Transplantation Immunology Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 9th Edition Chapter 17 p 359-383
9 Immune Tolerance and Autoimmunity Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 9th Edition Chapter 15 p 315-338
10 Immune Regulation Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 9th Edition Chapter 9 and 15 p 211-213, 315-339
11 ID of a Cancer Cell and the Concept of a Cancer Stem Cell. Devita, Hellman, and Rosenberg's Cancer: Principles and Practice of Oncology Chapter 1 p:44-64. Also related current reviews will be provided before lecture
12 Tumor Dormancy Yuzhuo Wang and Francesco Crea Tumor Dormancy and Recurrence. Also Related current reviews will be provided
13 Tumor Immunology Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 18 p 397-417
14 Immunotherapy of Cancer Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 18 p 390-397
15 Semester Review
16 Final Exam
Course Notes/Textbooks
Suggested Readings/Materials

 

EVALUATION SYSTEM

Semester Activities Number Weigthing
Participation
Laboratory / Application
Field Work
Quizzes / Studio Critiques
Portfolio
Homework / Assignments
1
20
Presentation / Jury
Project
1
40
Seminar / Workshop
Oral Exam
Midterm
Final Exam
1
40
Total

Weighting of Semester Activities on the Final Grade
3
60
Weighting of End-of-Semester Activities on the Final Grade
1
40
Total

ECTS / WORKLOAD TABLE

Semester Activities Number Duration (Hours) Workload
Course Hours
(Including exam week: 16 x total hours)
16
3
48
Laboratory / Application Hours
(Including exam week: 16 x total hours)
16
Study Hours Out of Class
15
1
15
Field Work
Quizzes / Studio Critiques
Portfolio
Homework / Assignments
1
5
Presentation / Jury
20
Project
1
Seminar / Workshop
Oral Exam
Midterms
Final Exams
1
32
    Total
100

 

COURSE LEARNING OUTCOMES AND PROGRAM QUALIFICATIONS RELATIONSHIP

#
Program Competencies/Outcomes
* Contribution Level
1
2
3
4
5
1

Explain the normal structure and functions of the human body at the molecular, cellular, tissue, organ and system levels, associate them with suggestions, practices and clinical situations (nutrition, exercise, vaccination, mental health, etc.); to protect and improve the health of individuals.

X
2

Describe the mechanisms of diseases at the molecular, cellular, tissue, organ and system levels and make evidence-based decisions by associating them with disease findings, diagnosis and treatment approaches.

X
3

Consider the ethical principles, scientific facts, legal regulations and the biopsychosocial and cultural characteristics of the patient in the medical decision making process. Place importance and respect the autonomy of patients and the confidentiality of patient information, within the framework of the law and the provisions of healthcare application standards.

4

Prioritize patient safety to minimize malpractice by carrying out risk assessment, take the necessary precautions, perform the necessary medical practice and record them.

5

Communicate healthily, openly and effectively with healthcare workers, patients and their relatives, with the communication structured on empathy and care, trust and constructiveness; while being respectful to language, belief, race and cultural characteristics.

6

By bearing in mind the patients’ values, beliefs, priorities, and needs; provide evidence-based options and include them in the decision making process.

7

Preserve our planet’s resources and consider its effects on the public and individual’s health, advocate to disseminate healthy lifestyle behaviors and modify factors that affect health adversely.

8

Reach current, valid and reliable information effectively using technology. Critically evaluate this information for solving problems in an evidence-based medical decision-making process, bearing in mind prevention, diagnosis, and management of diseases.

X
9

Identify problems, create hypotheses, conduct research and employ teamwork to analyze results for generation and dissemination of health-related scientific knowledge.

X
10

By taking feedback and evaluating their performance, determine the areas and options for improvement and implement them within a plan.

X
11

Care for their own personal health, safety and appearance, take the necessary precautions in order to set an example for their colleagues and society.

12

Continuously renew themselves in their medical knowledge by always bearing in mind their commitment to lifelong learning principles.

13

Using various communication tools, share their professionally gained knowledge in the field of healthcare, opinions, experiences, and evaluations with institutions, colleagues and the public.  Advocate for healthcare and contribute to developing policies to protect and improve it.

X

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest